If you’ve been researching weight loss injections, you may have come across Mounjaro, the newest treatment making headlines in the UK. As a pharmacy offering professional support for weight management, we’ve received increasing interest in how Mounjaro works and what kind of results patients can realistically expect. While search terms like “mounjaro reviews” are on the rise, it’s important to understand that the most reliable information comes from clinical trials and medical guidance.

At Vivo Pharmacy, we believe in setting realistic expectations. In this post, we’ll walk you through what typically happens during the first 1, 3, and 6 months of using Mounjaro (tirzepatide), based on clinical data—not hype. Everyone’s experience is unique, but this timeline will give you a clear idea of what to expect if you’re considering starting your weight loss journey with Mounjaro.

What Is Mounjaro?

Mounjaro is a once-weekly injection containing tirzepatide, a dual-action medication that mimics two naturally occurring hormones in your body: GLP-1 and GIP. These hormones help regulate appetite, blood sugar levels, and insulin production. Unlike earlier treatments that only targeted GLP-1 (such as Wegovy), Mounjaro engages two pathways—often leading to stronger appetite suppression and more significant weight loss.

It has been approved in the UK for weight management in adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol.

Month 1: Starting Off Gently

During the first month, most patients begin on the lowest starting dose of Mounjaro (usually 2.5mg once weekly). This low dose helps your body adjust to the medication and reduces the risk of side effects such as nausea, bloating, or fatigue.

What to expect:

• –> Appetite may begin to reduce within the first two weeks

• –> You might start to feel fuller sooner after meals

• –> Weight loss is usually modest—often 2–5 pounds (1–2.5kg) in the first four weeks

• –> Some individuals notice digestive side effects as their body adjusts

It’s important not to be discouraged by the relatively slow start. This phase is designed for safety and tolerance. The dose will typically increase to 5mg in the second month, unless advised otherwise by a healthcare professional.

Month 3: Building Momentum

By month three, most patients are on 10mg or potentially higher doses (7.5mg or 12.5mg depending on individual progress). At this stage, the medication reaches a stronger therapeutic level, and the effects become more noticeable.

What to expect:

• –> Significant reduction in appetite and snacking

• –> Steadier, more noticeable weight loss—often 10–15 pounds (4.5–7kg) total since starting

• –> Increased energy and motivation from visible progress

• –> Improved portion control and greater awareness of eating habits

• –> Possible mild side effects during dose adjustments

This is when many patients report regaining control over food choices and feeling optimistic about their long-term weight loss goals. However, it’s still important to focus on maintaining a healthy diet and incorporating physical activity where possible, as Mounjaro works best when paired with lifestyle changes.

Month 6: Long-Term Progress and Results

After six months, clinical trials show that patients using Mounjaro can expect up to 15–20% total body weight loss, depending on their starting weight and adherence to the treatment plan. By this point, patients may be on the maximum dose of 15mg per week.

What to expect:

• –> Total weight loss ranging from 10kg to over 20kg, depending on baseline weight

• –> Noticeable changes in body shape, clothing size, and confidence

• –> Stabilisation of blood sugar (in patients with insulin resistance or type 2 diabetes)

• –> Fewer side effects as your body becomes fully adjusted to the medication

• –> Increased physical activity and improved overall well-being

Many people find that six months marks a turning point—not just in terms of the number on the scales, but in their relationship with food, energy levels, and daily routines. However, consistency is key. If you stop the treatment or return to old habits, weight regain is possible. That’s why ongoing support is so important throughout your journey.

Professional Guidance Matters

At Vivo Pharmacy, we provide more than just the prescription. Our weight loss consultations include:

• –> Eligibility assessments for Mounjaro and other treatments

• –> Dose scheduling and support through titration phases

• –> Lifestyle and dietary advice to enhance results

• –> Ongoing check-ins to monitor progress and adjust as needed

While you may have searched for “Mounjaro reviews”, what you really need is trusted, personalised guidance—and we’re here to provide it. Contact us for the support you need.

Ready to Start?

If you’re considering Mounjaro and want to understand how it fits into your weight loss goals, book a consultation with our pharmacy team today. We’ll guide you safely through every stage of your journey—whether your goal is one stone or several.

Sustainable weight loss starts with informed choices. Drop in today or book an appointment and let us help you make yours.

This blog was written on behalf of Vivo Pharmacy by Pharmacy Mentor.