South Africa offers a remarkable range of experiences, from wildlife safaris and wine tours to bustling cities and coastal escapes. With such variety, there is no single perfect time to visit for everyone. Your best travel dates depend on what you want to do and the health precautions you need to take. Depending on your destinations, you may need vaccines for hepatitis A, typhoid, and tetanus, and malaria prevention in certain areas.
At Vivo Pharmacy, we support travellers with the health advice and vaccinations they need for safe and memorable trips abroad. If you are planning a journey to South Africa, timing your visit is about more than just weather preferences or crowds. Certain seasons can carry different health considerations, so knowing the best time to travel to South Africa also means preparing for the illnesses you might encounter. Our travel health services in Bristol can help you stay protected wherever your adventure takes you.
January to March: Peak Summer Highlights
This is South Africa’s summer, with hot weather perfect for beach holidays in Cape Town or along the Garden Route. It is also a popular time for hiking in the Drakensberg Mountains and exploring the Winelands. However, warm weather and increased outdoor activity can bring higher exposure to insect bites in some rural areas, so malaria prophylaxis might be necessary if you are travelling to the low-risk zones in Limpopo or Mpumalanga.
During this season, vaccinations such as hepatitis A are recommended if you will be eating street food or dining in rural locations, where food hygiene standards can vary. Typhoid vaccination may also be useful for similar reasons. Our travel health services in Bristol can guide you through these choices and supply any medicines or vaccines you need before you go.

April to June: Cooler Weather and Fewer Crowds
Autumn in South Africa brings milder temperatures and fewer tourists, making it an ideal time for city sightseeing in Johannesburg, Cape Town, or Durban. Game viewing is still possible, and you may find better value for accommodation and tours.
With cooler weather, the mosquito population in certain areas tends to drop, reducing malaria risk, but vaccination planning remains important. Hepatitis B vaccination is worth considering if you are engaging in activities where blood contact could occur, such as volunteering in healthcare or certain sports. Rabies vaccination is advisable for travellers spending time in rural or wilderness areas where animal contact is possible.
At Vivo Pharmacy, we can tailor your vaccination plan to match your itinerary so that you travel with the right level of protection for your chosen activities and destinations.
July to September: Safari Season in Full Swing
These winter months are prime safari season in South Africa, particularly in Kruger National Park, where the dry weather means animals gather at waterholes, making them easier to spot. While cooler temperatures mean fewer mosquitoes, malaria risk is still present in some safari areas and preventive medication should be discussed.
Tetanus vaccination is important for all travellers, as minor cuts and scrapes from outdoor adventures can pose a risk if you are not up to date. We also recommend considering cholera prevention advice if you are visiting rural communities where water treatment may be unreliable. Our travel health services in Bristol can supply both the vaccines and practical tips to keep you safe during your safari adventure.

October to December: Perfect for Mixed Itineraries
Spring and early summer bring warmer weather, blooming landscapes, and a mix of activities to suit different interests. This period is ideal if you want to combine wildlife viewing with coastal relaxation or city exploration.
However, the hotter and wetter conditions in some regions mean mosquitoes are more active, which increases the risk of malaria in affected provinces. We can help you choose the most suitable preventive medication and provide advice on insect repellents and clothing to reduce bites. Hepatitis A and typhoid vaccines remain important for travellers sampling a variety of local foods, and rabies vaccination may be relevant for those visiting rural reserves.
By planning your trip during these months, you can enjoy both cultural and natural highlights while protecting your health with the right preventive measures from our team.
Contact us to tailor your travel vaccination schedule, because each holiday is unique, and your itinerary, travel history, and medical needs can make a difference to your vaccination requirements.
Travel Vaccines Should Not Be One-Size-Fits-All
The best time to travel to South Africa depends on what you want to experience and where you are going. Each season offers something different, from summer beach escapes to winter wildlife spectacles. Alongside planning your activities, it is important to think about the health risks for each time of year. Vaccinations for hepatitis A, typhoid, tetanus, and rabies, as well as malaria prevention, may be recommended depending on your destinations and plans.
At Vivo Pharmacy, our travel health services in Bristol are here to make your trip as safe as it is memorable. By booking an appointment well ahead of your departure, you can ensure you have all the vaccines, medications, and health advice needed for a confident and healthy journey through South Africa.

This blog was written on behalf of Vivo Pharmacy by Pharmacy Mentor.
